What are the Treatments for Peyronie's Disease?

What are the Treatments for Peyronie's Disease?

Peyronie's disease is a medical condition in which men are affected by a curve or bend in their penis. This usually happens due to the formation of scar tissues or plaques in the penis due to previous trauma or injury to the penis.

Doctors may suggest different treatment options based on the severity of one's condition. Peyronie's disease treatment includes:


Pentoxifyllin is an effective oral medicine used to reduce the number of scar tissues and straighten the penis. Some doctors may also suggest vitamin E supplements, topical medications, and coenzyme Q10 to improve the symptoms caused by Peyronie's disease.


Collagenase clostridium histolyticum (Xiaflex) is a drug that is injected into the penis. This medicine helps in breaking down the collagen buildup and is found effective when used along with a process known as modeling in which the curved penis is bent in the opposite direction of the curve. Another medicine used for injecting into the penis is the Verampil which has also shown to be able to decrease the curve and the pain in many men.


When none of the medication works, the doctor considers surgery as a treatment option in order to stop it from getting worse. There are commonly three types of surgical methods used for Peyronie's treatment. It includes:

Plaque Excision or Incision with Grafting

In this type of surgery, the surgeon removes the scar tissues and grafts it with the tissues of one's own body or another human or animal. The surgeon also makes one or more cuts in the scar tissue and stretches to release the tightness. This procedure is done in the severe cases of penile deformity as there is a high risk of causing numbness and erectile dysfunction.

Suturing the Unaffected Side

Here, the longer or the unaffected side of the penis is sutured to match with the side shortened by the scar. This procedure helps in straightening of the penis but can be used in less severe curvatures as it may result in a shortened penis.

Penile Prosthesis

The surgeon here inserts penile implants in place of the rod-like tissues inside the penis that are responsible for an erection. This semi-rigid implant needs to be manually bent upward for sexual intercourse and downward during other times. Apart from these, there are two cylindrical implants placed inside the penis and a small pump inside the scrotum. In this condition, one gets an erection by pumping the scrotum.