When Is Clomiphene Citrate Used During Fertility Treatment?

When Is Clomiphene Citrate Used During Fertility Treatment?

Clomiphene citrate, also known as Clomid is a commonly used drug for treating female infertility. If a woman gets diagnosed with infrequent or absent ovulation, then the use of Clomiphene citrate can induce ovulation.

When Is Clomid Used?

Your doctor might prescribe Clomiphene citrate as the first-line treatment in the following cases:

How Does Clomid Work?

The Clomiphene citrate blocks the effect of oestrogen hormone, which lowers the oestrogen level in your body. This signals the pituitary glands to increase the follicle stimulating hormone or FSH and luteinizing hormone or LH, which are essential for ovulation. FSH stimulates the growth of ovarian follicle and LH triggers the release of matured egg that travels down the fallopian tube.


Your doctor performs a battery of tests, before starting this drug therapy. Usually, a course of Clomid starts from the 2nd to 5th day of menstrual flow. A low dose of 50 mg daily for five days is the usual course up to 3 cycles. If ovulation doesn't happen in the first cycle, then it may be suggested to increase the dose for the next cycle. You would also be closely monitored with some blood works and scans to know how your body responds to this drug therapy.


Using Clomiphene citrate for treating infertility has a significant number of benefits such as:

  • Cost-effective
  • Being an oral medication, it's non-invasive treatment.
  • Relatively fewer side effects
  • Your regular OB-GYN or primary care provider can prescribe this drug, thus reducing the hassle of reaching to a reproductive specialist.